Mucopolysaccharidosis type Ⅶ

This type is also called Goldberg syndrome (Goldberg) syndrome, glucuronidase deficiency. It is characterized by normal or slightly retarded intelligence, skeletal changes, special face, dwarf, hepatosplenomegaly, and hernia. Excess dermatan sulfate can be excreted in the urine, which is an autosomal recessive disease. Although the biochemical defects are the same, the clinical manifestations and age of onset are different in each case.