Gittling syndrome

Gitlin syndrome (Gitlin syndrome) disease gene is located on the X chromosome, and is a sex-linked recessive hereditary severe combined immunodeficiency disease. The pathogenesis is uncertain. The patients are mostly men, and are susceptible to upper respiratory tract infections, otitis media, pyoderma, cutaneous mucosal candidiasis and viral infections. Diagnosis is based on genetic investigations and X chromosome tests. For treatment see severe combined immunodeficiency disease. Most children die in early childhood, but the survival time is longer than severe combined immunodeficiency disease.