Spinal metastases

Spinal metastatic cancer can cause a group of symptoms, including pain, mobility or autonomic dysfunction, and sensory disturbances, which are mainly determined by tumor growth rate, bone involvement and destruction, nerve compression and systemic disease. Rapid tumor growth can cause rapid progression of symptoms. Dissolved tumors can cause pathological fractures or deformities due to bone destruction. Metastatic tumors can also cause nerve root involvement and spinal cord compression, which in turn can cause radiculopathy and myelopathy. It also shows signs of systemic disease, including weight loss, loss of appetite, or organ failure. For cases of large metatarsal metastases, obvious paravertebrae and even rectal masses can be found on physical examination.