Anti-Helicobacter IgG antibody

Helicobacter pylori infection is an important cause of chronic gastritis. Helicobacter pylori-associated chronic gastritis can cause local and systemic immune responses to H. pylori. After H. pylori infection, humoral immunity produces H. pylori antibodies. This reaction constitutes the specific identification of HP antibodies in serum. Basic, and attempt to diagnose and evaluate the efficacy by serological methods. There are currently many commercial ELISA kits for detecting the status of HP antibodies, which use different antigens. Although the literature related to the manufacture of the kit often reports high sensitivity and specificity; independent studies have shown that some The sensitivity and specificity of a particular kit vary considerably from study to study, so any laboratory that expects to use serology to diagnose HP infection should ensure that the kit it uses is highly sensitive and specific And have been properly validated in the population tested.