Plasma cell

Plasma cells: oval, 8-20 μm in diameter. The nucleus is round and obviously eccentric. The purple-red chromatin becomes a coarse clot and is arranged in a wheel shape (some cells may have 2 to 4 nuclei under pathological conditions). The cytoplasm is rich, gray-blue, and some are lilac flowers. Sometimes there are many vesicles, but there are a few azure particles. There is a clear semi-circular blank area near the core. In addition, there are occasionally multiple lamellae in the cytoplasm, and the endoplasmic reticulum in the cytoplasm expands, breaks, or becomes round. Finally, a vacuole was formed, which can be seen from small to large on the smear. Until they become large vacuoles; and see various transitional cells containing these vacuoles, these degenerate cells are eventually engulfed by macrophages. These cells increase during aplastic anemia. In addition, plasma cells and juvenile plasma cells can also appear in the blood, which is caused by antigen stimulation or certain infectious diseases, especially in rubella, there can be various plasma cells. Plasma cells can appear in blood films during infectious mononucleosis, epidemic hemorrhagic fever, toxoplasmosis, syphilis, tuberculosis and other diseases.