Serum immunoglobulin M

IgM accounts for 6% of the total serum immunoglobulins, and is mainly present in blood vessels. It is the first antibody produced by the body after being stimulated by the antigen. Because IgM is mainly present in blood vessels, it is the first-line antibody against intravascular infections and plays an important role in preventing the occurrence of sepsis. Clinically, IgM is commonly measured by ELISA. ELISA is an abbreviation for Enzyme-Linked Immunosorbnent Assay. It is an immunoenzyme technology developed after immunofluorescence and radioimmuno technology. ELISA is a highly sensitive test technique that combines the specific reactions of antigens and antibodies with the highly efficient catalytic action of substrates on the basis of immunological reactions. As the reaction of antigen and antibody is performed in the wells of a solid-phase carrier & mdash; & mdash; polystyrene microtiter plate, after each reagent is added for incubation, excess free reactants can be removed by washing to ensure the test results. Specificity and stability.