Vitamin K

Vitamin K (VitK for short) is also called anti-hemorrhagic vitamin, which is a chlorophyll quinone biologically active & alpha ;, a general term for methyl-1,4-naphthoquinone derivatives. (Menaquinones). The chemical form of VitK1 is 2-methyl-3-phytyl 1,4-naphthoquinone, also known as 2-methyl-3-chlorophyll-1,4-naphthoquinone; and VitK2 (abbreviated as MK-n ) Are a series of compounds, collectively known as menaquinones, which have an unsaturated polyisoprenyl group on the side chain. There are various forms depending on the length of the side chain. The most common is 6 to 10 classes on the side chain. The isoprenyl menaquinone (from MK-6 to MK-10), its structural formula is shown in Figure 1. In addition, VitK3 (2-methyl-1,4-naphthoquinone), which is synthesized in vitro, has no activity by itself, and can be alkylated to MK4 in the liver in vivo and has biological activity. VitK is a derivative of naphthoquinone. It is heat-resistant and acid-resistant. It is a fat-soluble vitamin, insoluble in water, but easily damaged by sunlight and alkali. VitK1 is a bright yellow oil, VitK2 is a bright yellow crystal, soluble in methanol, acetone, benzene, petroleum ether, chloroform, etc. VitK3 is a yellow crystal, soluble in carbon tetrachloride, chloroform, vegetable oil, acetone, benzene and ethanol. Derivatives of VitK such as VitK3 phosphate, succinate or bisulfite are water-soluble, while methyldioquinone acetate is not sensitive to light.