Vascular hemophilia

Vascular hemophilia, also known as VonWillebrand syndrome (VWD). VonWillebrand factor (VWF for short) in patients with this disease is deficient or the molecular structure is abnormal. The performance of typical cases is: ① prolonged bleeding time. ② Platelets have reduced adhesion to glass beads and weakened or non-aggregated ristomycin aggregation function. ③Plasma factor 有关 related antigen (ⅧR: Ag) and coagulation activity (Ⅷ: C) decreased or VWF activity (ⅧR: VWF) decreased. VWD is a more common type of hereditary hemorrhagic disease that can be affected by both men and women. Most patients are autosomal dominant and a few are autosomal recessive. VWF is located on chromosome 12.