Pediatric Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a type I of histiocytosis. Langerhans cell histiocytosis is a kind of dendritic cell proliferative disease of monoclonal origin, which has multiple clinical manifestations. The lesions can be focal or diffuse. Syndromes with widely varying lesions. So far, the cause is unknown. With the advancement of chemotherapy methods, the prognosis of this disease has been significantly improved in recent years. The incidence of this disease is low. Infants and children are the main population. Male patients are the most common disease, and they are also seen in adults and even the elderly.