Blood urea nitrogen to creatinine ratio

Scr and BUN can reflect the degree of damage to glomerular filtration function to a certain extent. BUN is also affected by extra-renal factors, such as high protein diets, gastrointestinal bleeding, dehydration, and high catabolism, which can cause BUN to increase. In the case of stable exogenous creatinine intake and constant creatinine production in the body, Scr mainly depends on the filtering ability of the glomerulus, so it is more accurate than BUN. Therefore, the observation of the ratio of serum urea nitrogen to creatinine has certain clinical significance.