Protein of the week

This week's protein is a light chain monomer or dimer of an immunoglobulin. It belongs to incomplete antibody globulins and is divided into κ and λ types. The molecular stars are 22000 and 44000, respectively. There is an M-band in some parts of the protein band, which is mostly located between the γ-band and β-γ-band. Easily excreted from the kidney called light chain urine. It can be filtered through the glomerular filtration membrane. If the amount exceeds the limit that the proximal tubule can absorb, it is excreted from the urine, and the excretion rate in the urine is more than albumin. Renal tubules have reabsorption and dissimilation effects on this week's proteins. When excreted by the kidney, they can inhibit the reabsorption of other protein components by the renal tubules, and can damage the proximal and distal curved tubules, thus leading to renal dysfunction and the formation of proteinuria. At the same time albumin and other protein components are excreted. This week, the protein can be coagulated when heated to 40-60 ° C, and can be redissolved when the temperature rises to 90-100 ° C, so it is also called coagulated protein.