Neonatal sepsis

Septicemia of newborn refers to the invasion of the newborn's blood circulation by various pathogens during the neonatal period, where it grows and reproduces, produces toxins, and causes systemic infection. The incidence of neonatal disease and mortality are high. With the deepening of systemic inflammatory response syndrome research, the definition of sepsis is also expanding, including systemic inflammation and infection caused by endogenous infectious factors (such as intestinal flora). Neonatal sepsis generally refers to a pathological process in which bacteria are present in the blood and continue to reproduce. Positive bacterial results can be obtained through blood culture. When there is evidence of a bacterial-immunological diagnosis, but no positive blood culture result is obtained. A diagnosis can also be made. It is still a very important disease in the neonatal period, and its incidence accounts for about 1permil; ~ 10permil; and the incidence is higher in preterm infants.