T4 lymphocyte subsets

There are many antigens on the surface of T lymphocytes, among which there are many types of cluster differentiation (CD) antigens. These antigens not only mark cell types and differentiation stages, but also have certain functions, or serve as receptors, adhesion molecules, and signal transmission components Subgroups can be identified by these surface-specific antigens. At present, more monoclonal antibodies against differentiation antigens, such as anti-CD4 monoclonal antibodies, are used to detect peripheral blood mononuclear cells, and the subgroup distribution is determined according to the positive rate. T lymphocyte subsets are an important way to observe the body's cellular immune level, and are of great value in the diagnosis, treatment, and prognosis of malignant tumors, autoimmune diseases, immunodeficiency, and hematological diseases. T cell subpopulations have mutual restraint and mutual assistance effects. The increase or decrease of any one of them affects the formation of the other subpopulation.