Glucagonoma

Glucagonoma (GCGN) is an islet A (α2) cell tumor that secretes excessive glucagon, which is mainly manifested by skin migration, necrotizing erythema, diabetes, anemia, tongue and angular inflammation, vulva Vaginitis, hypoamino acidemia, etc., also known as hyperglycemia skin disease syndrome. Malignant, often metastasized early. Tumor diameter is generally 1.5 to 3 cm, and sometimes the entire pancreas is a tumor. After early surgical removal of the tumor, skin damage and diabetes can quickly disappear. This disease is more common in middle-aged and elderly people aged 40 to 70 years. Women are more common than men, and most of them are menopausal women. Most have a course of more than 1 year, and some exceed 12 years.