Amniotic fluid alpha fetoprotein

Amniotic fluid alpha-fetoprotein is a glycoprotein that is synthesized mainly in the liver of the fetus with a molecular weight of 69,000. AFP accounts for 1/3 of the total plasma protein at 13 weeks of the fetus. It reaches the highest peak at 30 weeks of gestation, and then gradually decreases. The plasma concentration at birth is about 1% of the peak period, about 40 mg / L, which is close to the adult level at the age of age (less than 30 μg / L).