surface charge on red blood cells

The surface of the red blood cells is negatively charged. The negatively charged red blood cells are placed in the electric field, and they will move toward the positive electrode. Under the same electric field strength and suspended ion intensity, the faster the cell moves, the higher the cell surface charge density. The opposite is the lower. The main effect on the surface charge of red blood cells is the amount of sialic acid on the erythrocyte membrane. The more the substance, the more negative charge. At present, the detection method of the surface charge of red blood cells is mainly detected by using an invisible capillary cell electrophoresis apparatus. There are two expressions of the value, one is the cell electrophoresis time, and the other is the cell electrophoresis rate. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether fasting: fasting Tips: After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately lying down, drink a small amount of sugar water, and then undergo a physical examination after the symptoms are relieved. Normal value The electrophoretic rate of normal human red blood cells in plasma was 1.16±0.06μ·S-1·V-1·cm-1. Clinical significance Abnormal results erythrocyte electrophoresis rates were reduced in patients with ischemic stroke, hemorrhagic stroke, coronary heart disease, myocardial infarction, and systemic lupus erythematosus. People who need to be examined have fever, fatigue, loss of appetite, general malaise, joint swelling, muscle aches or signs of stroke. Precautions Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood is drawn, blood is taken for examination, and venous blood is generally taken, and blood is drawn by a doctor or a nurse. The amount of blood drawn is determined according to the difference of the test content and the number of items. The blood volume is generally 2-20 ml, and the maximum is not more than 50 ml, and then analyzed by an invisible capillary cell electrophoresis apparatus. Not suitable for the crowd Hemophilia and diffuse intravascular coagulation. Adverse reactions and risks Do not touch the dirt after blood collection. Do not wash your hands immediately to avoid infection.