Arsenic poisoning
Introduction
Introduction to arsenic poisoning Arsenic poisoning, often called arsenic poisoning, mostly due to misuse or excessive toxic poisoning. Inhalation of powder, smoke or contaminated skin poisoning during production and processing is also common. Arsenic trioxide can be killed by inhalation of 5 to 50 mg orally from 60 to 100 mg. Generally, due to the excessive dose of arsenic-containing drugs, it can also be caused by eating arsenic-containing venoms, snails, insecticides, and fruits and vegetables that have just been sprayed by such insecticides. , livestock and so on. basic knowledge The proportion of sickness: 0.01% Susceptible people: no specific population Mode of infection: non-infectious complication:
Cause
Causes of arsenic poisoning
Arsenic poisoning is generally caused by the excessive dose of arsenic-containing drugs. It can also be caused by eating arsenic-containing venoms, snails, insecticides, and fruits and vegetables that have just been sprayed by such insecticides. , poisonous dead poultry, livestock meat, etc., arsenic trioxide (also known as arsenic, red, white stone, etc.) is commonly used in the rural areas of northern China, killing pesticides, very toxic, its pure appearance and salt, sugar, Flour, gypsum, etc., can cause poisoning due to ingestion, misuse, and poisoning due to well water and food contaminated with arsenic trioxide. Mother poisoning can cause fetal and milk poisoning.
Prevention
Arsenic poisoning prevention
1. Arsenic poisoning is usually ingested through the digestive tract, so pay attention to the usual diet and avoid contact with these heavy metals is the fundamental way to prevent poisoning.
2. Eat more food to avoid damage to the liver and other foods, light diet, eat more blood food, such as jujube, animal liver, etc., rich in vitamins and antioxidant foods. Eliminate patients' anxiety and pessimism. Encourage patients and give them confidence.
Complication
Arsenic poisoning complications Complication
Peripheral neuritis is complicated by infection or inflammation in most cases, and is also called peripheral neuropathy. The disease is caused by a variety of causes of peripheral neuropathy (including cranial nerves and spinal nerves), manifested as sensory, motor and autonomic dysfunction within the range of damaged innervation, multiple or singular, symmetrical or asymmetrical Is a more common disease of the nervous system. It can occur at any age.
Symptom
Symptoms of arsenic poisoning Common symptoms Nasal dyspnea, exfoliative dermatitis, nausea, nail abnormalities, polyneuritis, diarrhea, fingernails, nail color change, abdominal pain, nail tarnishing and...
Oral acute arsenic poisoning early common gastrointestinal symptoms, such as mouth and throat dry, pain, burning, tightness, hoarseness, nausea, vomiting, difficulty in swallowing, abdominal pain and diarrhea, vomit first stomach content and rice bran water Then, mixed with blood, mucus and bile, sometimes mixed with small pieces of unabsorbed arsenic; vomit can have a garlic-like odor, severely resembles cholera, begins to drain a large amount of watery stool, and later becomes bloody, or Rice bran water sample mixed with blood, quickly dehydration, acidosis and shock, but also headache, dizziness, irritability, convulsions, toxic myocarditis, polyneuritis, etc., a few have nasal and skin bleeding, serious sick children can Respiratory, circulatory, liver, kidney and other functional failures and central neuropathy occur 24 hours to several days after poisoning, and there are critical signs such as dyspnea, convulsions, coma, etc. A small number of patients may experience shock within 20 minutes to 48 hours after poisoning. Even death, and gastrointestinal symptoms are not significant, sick children may have hemoporphyria attack, urinary biliary original strong positive.
Hydrogen sulphide poisoning often has hemolysis. When subacute poisoning occurs, symptoms of polyneuritis appear. The limbs feel abnormal. First, pain, numbness, then weakness, weakness, until complete paralysis or incomplete paralysis, wrist sag, foot sag and sputum Reflex disappears, etc.; or difficulty in swallowing, pronunciation and breathing disorders, due to vasomotor dysfunction, sometimes skin flushing or erythema, chronic poisoning patients often manifest as weakness, loss of appetite, occasional nausea, vomiting, constipation or diarrhea, etc. , white blood cells and thrombocytopenia, anemia, red blood cell and bone marrow cell formation disorders, hair loss, stomatitis, rhinitis, nasal septum ulcers, perforation, skin pigmentation, exfoliative dermatitis, excessive keratinization of palm and toe skin, nails Loss of luster and flat state, thin and brittle, white stripes appear, and liver and myocardial damage, arsenic in patients with poisoning, increased arsenic and arsenic levels in urinary arsenic and finger, and a large amount of arsenic in oral administration. X-ray examination revealed substances in the gastrointestinal tract that could not be penetrated by X-rays.
Examine
Arsenic poisoning
According to the occupational history of close contact with arsenic for a long period of time, dermatitis, hyperkeratosis of the skin, skin pigmentation and digestive system, nervous system-based clinical manifestations, reference to laboratory results such as arsenic, comprehensive analysis, exclusion of other causes Cause similar diseases; can be diagnosed.
Has headache, dizziness, insomnia, multiple dreams, fatigue, indigestion, weight loss, liver discomfort and other symptoms; arsenic exceeds the local normal reference value.
Diagnosis
Diagnosis and identification of arsenic poisoning
It can be diagnosed based on medical history, clinical symptoms and laboratory tests.
Chronic mild poisoning
a) hyperkeratosis of the skin, especially in the palmar area;
b) diffuse black or tan pigmentation and pigmentation loss on the trunk and limbs;
c) mild liver damage;
d) mild peripheral neuropathy.
Chronic severe poisoning
On the basis of chronic mild poisoning, one of the following manifestations:
a) cirrhosis;
b) peripheral neuropathy with limb dyskinesia or limb paralysis;
c) Skin cancer.
