acetanilide poisoning
Introduction
Introduction to acetanilide poisoning Commonly used in this class of drugs are phena-cetin (para-cetin) and paracetamol (paracetamol), others are compound aspirin tablets containing phenacetin, pediatric antipyretic tablets, chlorpheniramine tablets, anal granules, excellent dispersion Pain tablets, painkillers, stagnation tablets, painkillers tablets, Antong tablets, etc., most cases of poisoning due to a large number of frequent, frequent or long-term application; infants take a larger dose of pediatric fever tablets poisoning Responders are more common. Parkular pain is a metabolite of phenacetin, which is less toxic, but acute poisoning can occur if taken in large quantities. basic knowledge The proportion of illness: 0.002% Susceptible people: infants and young children Mode of infection: non-infectious Complications: shock
Cause
Causes of acetanilide poisoning
Poisoning is often caused by taking large doses or taking them for a long time.
Prevention
Acetanilide poisoning prevention
It is not advisable for newborns and babies to use this medicine. Patients with anemia, heart, lung, kidney and liver diseases are forbidden to apply this medicine for a long time.
Complication
Acetanilide poisoning complications Complications
In severe poisoning, the central nervous system is initially excited, and then turned into a state of inhibition. In severe cases, shock may occur.
Symptom
Symptoms of acetanilide poisoning Common symptoms Leukopenia nausea abdominal pain tremors tinnitus fainting exfoliative dermatitis fatigue proteinuria shortness of breath
In addition to nausea, vomiting, tinnitus, sweating, etc., the poisoned children are mainly characterized by purpura caused by methemoglobinemia, accompanied by hypoxic symptoms such as shortness of breath and increased heart rate; hemolytic anemia can occur at the same time. Hemoglobinuria, urine changed from bright yellow to red wine color, severe poisoning often has central nervous system excitability symptoms, such as agitation, convulsions and convulsions, etc., later turned into inhibition, sick children appear stupor and lethargy, or have blood pressure and body temperature drop Even shock occurs, long-term application may have headache, dizziness, abdominal pain, purpura, anemia, fatigue, agitation, insomnia and liver, kidney damage, occasionally acute renal failure, some sick children with drug rash, high fever, trembling, facial edema, Leukopenia, neutropenia, thrombocytopenia, occasional exfoliative dermatitis, Parker's heat pain is less toxic to the blood, excessive can cause severe liver damage, may cause liver necrosis or coagulopathy and encephalopathy after 2 to 5 days of misuse .
Examine
Examination of acetanilide poisoning
Methemoglobinemia, with leukopenia and neutropenia, can be analyzed in vomit.
Diagnosis
Diagnosis and identification of acetanilide poisoning
According to the medical history, clinical manifestations and laboratory data is not difficult to make a diagnosis.
Need to be differentiated from other antipyretic analgesic poisoning, including indomethacin, analgin, and acetaminophen and other drug poisoning.
