Anti-skeletal muscle antibody

Anti-skeletal muscle antibody is an antibody that can react with autoantigens such as α-actin and myosin, which are more common in the serum of patients with myasthenia gravis. In addition to high acetylcholine receptors (ACHR), patients with myasthenia gravis also have anti-skeletal muscle antibodies, anti-thymus antibodies, anti-thyroid antibodies, etc., and patients with thymus abnormalities. It reached 92%. The positive rate of ASA in non-complicated thymoma patients was 30%, and it could be negative after thymectomy. Therefore, anti-skeletal muscle antibodies are more valuable for the diagnosis of myasthenia gravis. In addition, ASA is sometimes seen in patients with rheumatoid arthritis and other collagen patients; the detection of ASA is of certain value for the immunosuppressive treatment of autoimmune complications after bone marrow transplantation. ASA is commonly used for indirect immunofluorescence detection.