Frequency of amniotic fluid fat cells

There are two types of cells in amniotic fluid. One type is mainly from the epidermal shedding of the fetus. The nucleus is small and dense. The ratio of nucleus to cytoplasm is 1: 8, with a high percentage of non-nucleated cells. , The nucleus is large, the nucleus to cytoplasm ratio is 1: 3. There are few cells in amniotic fluid before 12 weeks of gestation. After 32 weeks of gestation, there are fewer cells from amniotic membrane. At term, the number of non-nucleated polygonal cells from the fetus increases. Staining with 1.36mmol / L Nile Blue Sulfate can stain a part of the cells from the sebaceous glands into orange. The increase of these cells reflects the maturity of the fetus.