Cortisone test

If a normal person drinks a lot of water in a short period of time, due to the large amount of water absorbed, the blood is diluted, and the hypothalamus-pituitary gland secretes antidiuretic hormone, so the urine volume increases greatly, which is called "water diuretic effect". In addition to having a close relationship with blood circulation and kidneys, water urinary action is also mainly involved in regulation of vasopressin and glucocorticoids secreted by the adrenal cortex. When the adrenal cortex is dysfunctional, the glomerular filtration rate is reduced, and the hypothalamic-pituitary secretion increases when diuretic hormones are seen. There is a clear diuretic delay, and the maximum urine output per minute decreases (<10ml). This type of water diuretic reaction Defects can be corrected by glucocorticoids.