Plasma auxin mediator

Auxin mediator: The effect of auxin is achieved by inducing a growth-promoting peptide substance produced by hepatocytes and existing in plasma. Such substances are called auxin mediators. It can accelerate protein synthesis, increase collagen tissue, promote chondrocyte division, and accelerate cartilage growth and ossification. Auxin mediators are a class of peptide substances, with three subtypes of A, B, and C, all of which have insulin action. The auxin-C in plasma is induced by the growth hormone acting on hepatocyte receptors and inducing hepatocyte synthesis and release. The concentration of auxin-C in plasma does not change with the pulsed fluctuations of growth hormone secretion. Various factors that stimulate or inhibit the release of growth hormone cannot cause the concentration of growth-medium C to change in a short time, so its plasma concentration is relatively Stable. Plasma auxin-C assay can be used to analyze the growth hormone function status and to diagnose the dysfunction of auxin mediators caused by growth hormone receptor deficiency.