Tryptophan tolerance test

Tryptophan tolerance test is a liver function clearance test. When hepatocytes are damaged, the amount of this enzyme is reduced and the vitality is reduced, the tryptophan clearance is slowed, and the total tryptophan content in plasma is increased. When liver cell function was significantly reduced, albumin synthesis and carrying capacity decreased, the amount of free tryptophan increased significantly, and the ratio of free tryptophan (F) / total tryptophan (T) increased. When the liver is in a coma, the free tryptophan in plasma is significantly increased on fasting due to competition for albumin carriers such as free fatty acids.