Cerebellar electrical stimulation

Cooper found in 1973 that stimulation of the cerebellum had significant inhibitory effects on neural activity in the brain, medulla, and spinal cord. And can inhibit experimental chronic epilepsy and cerebral cortex-induced activities. Clinical physiology also confirms that stimulation of the cerebellum can inhibit H, V1, and V2 reflexes in the spinal cord (H reflexes are single synaptic reflexes in the spinal cord, and V1, V2 reflexes are multisynaptic reflexes in the spinal cord), while inhibiting thalamic and cortical evoked responses. So the first use of chronic cerebellar electrical stimulation to treat epilepsy was successful. Most scholars believe that the mechanism of action is that the cerebellum is stimulated, and it plays a role through activation of the brainstem reticular structure and thalamus inhibition. Cooper himself believes that cerebellar stimulation is an afferent nerve block. At present, there are two types of devices used for cerebellar stimulation: one is a radio frequency coupled stimulator. It consists of an implanted part (electrode, lead and receiver) and an external device (transmitter and antenna). Such as foreign Medtronic1743 cerebellum stimulator and domestically produced J-63 cerebellum stimulator developed by the author (Figure 1). The second is a cerebellum stimulator that can be fully implanted in the body, such as the Neurolith Model 601, which is a fully implanted lithium energy battery pulse transmitter.