Neonatal jaundice

Neonatal jaundice refers to the neonatal period (from the fetal birth of the umbilical cord ligation to 28 days after birth), due to the accumulation of bilirubin in the body, resulting in elevated blood bilirubin levels and the appearance of yellow staining of the skin, mucosa and sclera Symptoms, the disease is divided into physiological jaundice and pathological jaundice. Physiological jaundice in term infants occurs 2 to 3 days after birth, peaks in 4 to 5 days, subsides in 5 to 7 days, and no later than two weeks; preterm infants last longer, with the exception of mild loss of appetite, generally No other clinical symptoms. If jaundice occurs 24 hours after birth, it does not regress in 2 to 3 weeks, and even continues to deepen and worsen, or recurs after remission, or starts to appear after 2 weeks after birth. All are pathological jaundice. Serum total bilirubin in term infants exceeds 205.2 μmol / L (12 mg / dl), and preterm infants exceed 256.5 μmol / L (15 mg / dl) are called hyperbilirubinemia, which is pathological jaundice. Indirect bilirubin in term children exceeds 307.8 μmol / L (18 mg / dl), which has a higher chance of causing bilirubin encephalopathy (nuclear jaundice), damages the central nervous system, and is susceptible to sequelae.