Ankle depression edema

Edema refers to excessive fluid accumulation in the interstitial space outside the blood vessels, which is one of the common clinical symptoms. Unlike obesity, edema is manifested as a noticeable depression when a finger presses a part with less subcutaneous tissue (such as the front of the calf). When there is too much fluid accumulation in the subcutaneous tissue space, the skin is pale, swollen, and wrinkles become shallow, the local temperature is low, and the elasticity is poor. Depression is called pitting edema or frank edema.