Barrett's esophagus

Barrett's esophagus (BE) refers to a pathological phenomenon in which the stratified squamous epithelium in the lower part of the esophagus is replaced by a single layer of columnar epithelium, which may be accompanied by intestinalization or not. Among them, intestinal metaplasia is a precancerous lesion of esophageal adenocarcinoma. The broad concept also includes metaplasia or ectopic gastric epithelium of the esophagus, and columnar metaplasia. In order to distinguish it from the columnar epithelium of the gastric cardia mucosa in the lower part of the esophagus, the range of the lesion was above 75px at the junction of the gastroesophagus (GEJ). In recent years, the concept has been defined as the connection found at the junction of the esophagus and the gastric mucosa, which was found endoscopically and confirmed by pathology. The original squamous epithelium of any length above the line (GEJ) is replaced by a columnar epithelium.