Anti-HCVAg positive

Anti-HCVAg positive is one of the symptoms of non-cryoglobulinic glomerulonephritis (non-cryoglobulinemic MPGN) and membranous nephropathy. Hepatitis C virus (HCV) is a single-stranded RNA virus. It was first discovered in 1989. It is estimated that there are about 100 × 106 infected people worldwide, mainly through blood products and intravenous drug use. In the past 10 years, the understanding of the relationship between HCV infection and glomerular disease has gradually increased. It is now believed that HCV-related renal damage mainly includes: cryoglobulinemia glomerulonephritis (cryoglobulinemic MPGN), non-coldglobulin Non-cryoglobulinemic MPGN and membranous nephropathy (MN) Clinical diagnosis should have: 1. Presence of proteinuria or hematuria; 2. Serum hepatitis C virus RNA (HCV-RNA) positive, anti-HCVAg positive; 3. Presence of cold globulin and immune complexes, and HCV-RNA virus core antigen And IgG anti-HCV antibodies; 4. Renal biopsy showed severe monocyte infiltration and large glomerular immune complex deposition.