Increased histamine excretion in urine

Histamine is an active amine compound with a chemical formula of C5H9N3 and a molecular weight of 111. As a chemical conductive substance in the body, it can affect the response of many cells, including allergies, inflammatory reactions, gastric acid secretion, etc., it can also affect nerve conduction in the brain, causing effects such as wanting to sleep. After taking H1 receptor antagonists (that is, antihistamines), the metabolites are excreted in the kidneys for a few to tens of hours, and the excretion in urine accounts for a large part. This results in increased excretion of histamine in the urine.