Cortisol deficiency

Anterior pituitary hypofunction (Simon-Sheehan syndrome) is a clinical symptom of hypothyroidism caused by hypothyroidism and secondary hypogonadism, thyroid and adrenal cortex. Sheehan syndrome is a common pituitary disease that occurs in women of childbearing age and has a history of major postpartum hemorrhage and shock. Conreux and Kan report that Sheehan syndrome can occur not only in vaginal births, but also after cesarean section. Today's rising cesarean section rate should cause great attention from obstetricians. Postpartum hemorrhage causes pituitary ischemia and infarction. The pituitary gland is more sensitive to hypoxia, and vasospasm easily occurs in a high estrogen state. In addition, postpartum hemorrhage causes hypotension, which causes ischemic infarction of the pituitary. With the improvement of childbirth and nursing technology in recent years, the severe Sheehan syndrome has been significantly reduced, but mild symptoms often appear in the postpartum years to more than ten years, or may not be diagnosed for life without severe stress. In patients with Han syndrome, ischemic necrosis may occur in the pituitary gland (anterior pituitary gland), followed by fibrosis to form scars. The remaining normal tissues are hypochromic cells without secretory function, and the pituitary gland (post-hypophysis) is usually normal. . In Sheehan syndrome, hypogonadism and female ovaries shrink significantly. Uterine and breast atrophy. The secretion of various hormones caused by adenoid pituitary lesions is drastically reduced, and the secretion of thyroid hormones, adrenocortical hormones, sex hormones is insufficient.