Gas diffusion disorder

The process of alveolar and blood flow through the alveolar-capillary membrane (alveolar membrane) for gas exchange is a physical diffusion process. The amount of gas per unit time depends on the gas partial pressure difference on both sides of the alveolar membrane, the area and thickness of the alveoli, and the gas's dispersion constant. The dispersion constant is related to the molecular weight and solubility of the gas. In addition, the total amount of gas dispersion also depends on how long the blood is in contact with the alveoli. The amount of dispersion depends on the gas partial pressure difference, diffusion area, distance, time, molecular weight of the gas and its solubility in the dispersion medium. Emphysema and other lung tissue diseases, diffuse pulmonary interstitial fibrosis and other diseases can cause reduced diffuse function. Clinically, when diffuse dysfunction occurs in lung lesions, there is often a significant imbalance in ventilation / blood flow at the same time, and its consequences all lead to hypoxia.