Characteristic large toe exfoliation

Mucocutaneous lymphnode syndrome (MCLS), also known as Kawasaki disease, is an acute febrile eruptive pediatric disease with systemic vasculitis becoming the main pathological feature. In 1967, Dr. Tosaku Kawasaki of Japan first reported. Because the disease can cause serious cardiovascular disease, people have paid attention to it, and the incidence has increased in recent years. Of the hospitalized cases of rheumatic diseases in Beijing Children's Hospital in 1990, there were 67 cases of Kawasaki disease and 27 cases of rheumatic fever; in the same data of 11 hospitals in other provinces and cities Kawasaki disease is twice as much as rheumatism. Obviously, Kawasaki disease has replaced rheumatic fever as one of the main causes of acquired heart disease in children in China. Kawasaki disease is currently considered to be an immune-mediated vasculitis and is temporarily included in the chapter on connective tissue diseases.