Vacuoles in peripheral blood lymphocyte plasma

Vacuoles in the peripheral blood lymphocyte plasma are one of the symptoms based on the diagnosis of Nieman Pick's disease. Niemaoh-Pick disease (NPD), also known as sphingomyelin lipidosis, is a congenital glucose and lipid metabolism disease. It is characterized by full monocytes and the nervous system with a large number of foam cells containing sphingomyelin.