Tenderness at the lower end of the sternum

Tenderness at the lower end of the sternum is one of the important signs of leukemia. In addition, it can be found in malignant lymphoma and myeloproliferative diseases, but the latter two are relatively rare. Leukemia, also called blood cancer. When people have leukemia, especially acute leukemia, sternal tenderness becomes one of the important signs. According to clinical observation, the most obvious site of sternal tenderness in most patients is the lower part of the sternum, which is equivalent to the sternum in the fourth and fifth intercostal space. Medical scientists believe that the main cause of bone pain is due to the proliferation of leukemia cells in the bone marrow, which increases the volume pressure of the bone marrow cavity, and the infiltration of leukocytes into the periosteum to stimulate the sensory nerves. Anatomically, the sternum plate is very thin, the skin covering this part is also very thin, and the periosteum sensory nerves are also abundant. Therefore, it is very sensitive to touch pressure and often produces obvious tenderness.