Thrombotic neoplasms

Vegetation is a general term for various protrusions formed inside or outside the body or organ during pathological processes. Thrombotic neoplasms are more common in nonbacterial thromboendocarditis. Nonbacterial thrombotic endocarditis can affect any heart valve, mainly affecting the mitral and aortic valves. Second, the tricuspid valve neoplasms are mostly on the atrial surface, and the aortic and pulmonary valve neoplasms are mostly on the ventricular surface. The main pathological change of nonbacterial thromboendocarditis is the formation of aseptic neoplasm on the valve. The early change is that the collagen of the valve is degenerative due to allergies, vitamin deficiency, hemodynamic damage, and aging. Degeneration and stroma edema, followed by local exfoliation of the intima of the valve, expose collagen and stroma to the bloodstream. When the antibody is in a hypercoagulable state, platelets and the like easily adhere to its surface, forming nonbacterial thrombotic neoplasms. Most of the lesions are superficial, and there is often no inflammatory reaction locally. Once the neoplasms fall off, they can produce arterial embolism.