Pediatric Drug Dermatitis

Dermatitis medicamentosa, also known as drug eruption, refers to the inflammatory reaction of the skin or mucous membrane caused by drugs entering the body of the child through various routes (such as oral administration, injection, inhalation, or plugging). In severe cases, it may be accompanied by systemic damage, internal organ damage, and even death. Pediatric drug rash can be caused by allergies and non-allergic reactions, the latter refers to pharmacologically predictable, often related to the dose, and the former has nothing to do with pharmacological effects. It is the former type of drug rash discussed in this article, which mainly refers to those caused by drug allergies. However, rashes caused by local effects of the drug itself, such as the erythema response of amyl nitrite, are not included in the scope of this article.