Sjogren's syndrome nervous system damage

Sjögren's syndrome (Sj? Gren's syndrome, SS) is a chronic inflammatory autoimmune disease mainly involving damage to exocrine glands. Micklicz first reported the disease in 1892. In 1933, Sj? Gren conducted a more detailed study, so it is also called Micklicz-Sj? Gren syndrome. The disease is caused by damage to the lacrimal gland and parotid gland and inflammatory cell infiltration. It is mainly characterized by dry mouth and dry eyes, and it can show multiple systemic and multi-organ damage throughout the body. It can be associated with other connective tissue diseases such as rheumatoid arthritis, systemic Lupus erythematosus, dermatomyositis, and scleroderma overlap. SS is often associated with multiple types of damage to the nervous system, and even neurological damage is the main clinical manifestation, such as peripheral neuropathy and myopathy.