Giant cell tumor of maxillofacial bone

Giant cell tumor of bone is mainly composed of multinucleated giant cells and smaller spindle-shaped or circular interstitial cells. The giant cells are large and contain many nuclei. Sometimes they can range from dozens to hundreds of spindle-shaped or circular cells. Morphology of Plasma Cells. The distribution and arrangement are the main basis for determining the properties of giant cells. Generally, this tumor is divided into three grades, one is benign, the second is potentially malignant, and the third is malignant. Macroscopically, giant cell tumors are granulous tissues that are prone to bleeding, without capsules, because of easy bleeding and necrosis. Changes in hemoglobin can make the tumor red-brown or green, hematoma fibrosis makes the tumor gray-white, tumor tissue necrosis, can make the tumor yellow or form a pseudocyst, the capsule may contain gelatinous or brown liquid, during the tumor progression In the middle, the bone destruction and regeneration alternated repeatedly, so the cortical bone expanded outwards and became thinner, and was eventually punctured by the tumor.