Hereditary chronic progressive nephritis in children

Hereditary nephritis, also known as Alports syndrome (AS), is a familial chronic progressive nephritis. The clinical features are mainly hematuria, and some cases can be expressed as proteinuria or nephrotic syndrome. Often accompanied by neurological hearing impairment and progressive renal dysfunction. And with the rapid development of molecular biology in the past 10 years, the study of AS has entered the molecular level and the gene level. Nowadays, the understanding of its genetic methods, clinical manifestations, and pathological characteristics is relatively clear.