Follicular gland cell proliferation syndrome

Follicular gland cell proliferation syndrome refers to a group of symptoms in which a patient develops a series of symptoms and signs such as female virilization, and has pathological changes of ovarian bubble cell proliferation. The eigen was described by Culiner and Shippel as early as 1949, indicating that there are luteinized vesicle cells in the stroma, but not related to adjacent follicles. This type of disease was originally included in polycystic ovary syndrome. The clinical manifestations are mainly masculine and more common in young women. Advances in steroid measurement methods and clomiphene's ineffectiveness have greatly helped the diagnosis of the disease. Pathology confirms the pathological changes of ovarian bubble cell proliferation, so this sign is currently independent, also known as ovarian bubble proliferative syndrome.