Hypermagnesemia

Hypermagnesemia occurs when the serum magnesium concentration exceeds the normal value. Refers to blood [Mg2] above 1.05mmoL / L. Except for a few iatrogenic factors that cause too much magnesium to enter the body, most of them are caused by decreased excretion caused by renal dysfunction. Like hypomagnesemia, serum magnesium concentration is not a reliable indicator of magnesium increase, because 25% of the magnesium in serum is bound to proteins, and this part of magnesium does not exert physiological effects; magnesium ions are mainly in cells, so when the body's magnesium is When the content increases, serum magnesium can be in the normal range. But in general, the degree of hypermagnesemia is consistent with the increase in magnesium in the body. Just as the kidneys have a certain delayed effect on the regulation of sodium, potassium, and bicarbonate ions, the regulation of the kidney on magnesium does not play a significant role quickly. Therefore, a large number of intravenous magnesium preparations can also occur if they are not monitored Hypermagnesemia. If renal dysfunction is combined and the regulating effect of the kidney is severely weakened, hypermagnesemia is prone to occur.