Diffuse palmoplantar keratosis

Diffuse palmoplantar keratodermia (also called hereditary palmoplantar hyperkeratosis), palmoplantar keratosis, palmoplantar keratoderma, Thost-Unna syndrome Most from the infancy. In the lighter cases, only the palms and palms have rough skin. In severe cases, palms and palms have diffuse plaques, thickened keratin on the edges, smooth appearance, yellowish yellow color that resembles palate, or wart-like thickening, and often causes cleft palate due to the disappearance of elasticity, causing pain.