Hereditary sensory neuropathy

Hereditary sensory neuropathy is classified as hereditary peripheral neuropathy, which is a group of diseases caused mainly by peripheral nerve damage caused by genetic factors. Hereditary sensory neuropathies are mostly dominant, and are typically manifested as recurrent painless ulcers on the extremities of the limbs caused by sensory loss, and gait instability caused by lack of deep sensory. Hand and foot ulcers and secondary osteomyelitis, osteolysis and cellulitis. Dyskinesias are not obvious. Mainly include: ① mutilating hereditary sensory neuropathy in adult; ② mutilating hereditary sensory neuropathy in childhood; ③ congenital insensitivity to pain 3 subtypes. Because hereditary sensory neuropathy often has severe autonomic nerve involvement, the above three subtypes and familial dysautonomia are collectively referred to as hereditary sensory autonomic neuropathy.