Progressive lateral atrophy

Progressive hemifacial atrophy is also called Parry-Romberg syndrome. It is a progressive dystrophic disease with unilateral tissues. A small number of lesions involve the limb or body, which is called progressive hemi atrophy. Its clinical features are chronic progressive atrophy of focal subcutaneous fat and connective tissue on one side of the face, muscle fibers are not affected, and severe cases invade cartilage and bones. Most scholars believe that this disease is related to sympathetic nerve dysfunction. The sympathetic nerve is damaged due to various reasons, which causes neurotrophic disorders in facial tissues and eventually causes facial tissue atrophy. Other theories involve local or systemic infections, injuries, trigeminal neuritis, connective tissue disease, genetic degeneration, etc. The rate of development of the course of disease is uncertain. Most cases tend to resolve after years to more than ten years, but the associated epilepsy may continue.