Pulmonary amyloidosis

Amyloidosis refers to a group of clinical syndromes with different manifestations. The common feature is that they all have extracellular amyloid deposits. Virchow first called the disease amyloidosis in 1854. This is because the deposited amyloid exhibits a similar dyeing reaction to starch when it encounters iodine and sulfuric acid. Yihong. The amyloids of different proteins have the same shape, and they are stained with Congo red and show specific green or yellow birefringence under polarizing lenses. Amyloid deposition can cause parenchymal cells to atrophy, interfere with the mechanical function of the organ, or affect vasoconstriction and cause bleeding. Amyloidosis can invade multiple or single organs and can be involved in all parts of the respiratory system. Extensive deposition of amyloid on the tongue can cause obstructive sleep disordered breathing; deposition on the tracheobronchial can cause airflow obstruction or bleeding; diffuse deposition of the interstitial lung can cause ventilation dysfunction and respiratory failure; pleural or diaphragmatic deposition Pleural effusion or weakness in respiratory muscles.