Premature pediatric disease

Progeria, also known as Hutchinson-Gilford syndrome, may be an autosomal recessive inheritance. Patients were more male than female, with normal growth and development within one year of age, and gradually changed premature senescence. It is a rare disease characterized by metabolic abnormalities, developmental disorders, and dwarfism, accompanied by incomplete development of bones, teeth, fingernails, hair, and fat. It is characterized by childhood appearance of the elderly and arteriosclerosis. Most of the children's intelligence is normal, but their blood lipids increase, and the production of growth hormone is reduced by 50% compared with normal.