Benign congenital flaccid syndrome in children

Congenital amyotonia syndrome includes a group of congenital neuromuscular diseases with different causes. As early as 1900, Oppenham reported a congenital disease in which most muscles were low in tension at birth, tendon reflexes disappeared, but there was no galvanic degeneration, and it was considered an independent disease at the time. In the future, two cases of congenital muscle relaxation and progressive spinal muscular atrophy occurred in the same family. It is believed that the pathology of the two diseases is exactly the same, with only slightly different symptoms, and an intermediate disease type between the two diseases. Finally, it is acknowledged that the congenital muscle relaxation described by Oppenham is a mild type of progressive spinal muscular atrophy. Benign congenital flaccid syndrome is congenital myodystony, also known as Oppenheim syndrome, benign congenital myopathy syndrome, and the like. This disease is a more benign type of congenital muscle flaccidity. It is characterized by weakening of most muscle tone and muscle weakness during infancy after birth.