Erythropoietic protoporphyria

Erythropoietic protoporphyrinosis is caused by low ferrochelase activity and elevated protoporphyrinogen IV levels, and is autosomal dominant. Most of the children develop the disease, with severe summer and mild winter, manifested as pain and burning sensation in exposed areas after sun exposure, erythema, edema, and wind masses. In severe cases, blisters, blood blister, erosion, and crusting may occur.