Occupational scleroderma

The disease refers to scleroderma-like changes caused by long-term repeated exposure to chemicals such as vinyl chloride and its polymers. Some patients may be accompanied by acral bone resorption, also known as acroosteolysis. According to reports, the disease mainly occurs in workers who cleaned the polyvinyl chloride solidified in the reaction pot by hand, so it is also called vinyl chloride disease, and the prevalence is 1% to 6%. The mechanism is unknown. Dinman et al. (1971) believe that the disease is a systemic rather than a localized disease.