Multiple epiphyseal dysplasia

Multiple epiphyseal dysplasia (muffiple epiphyseal dysplaais), also known as Fairbank disease or dysostosis epiphysealis multiplex, is a rare genetic defect of cartilage development, which is characterized by abnormal ossification of many epiphyses. Patients Obstacles to growth, short fingers. Fairbank first described the disease in 1935, with hereditary and family history. Men are more common than women. The age of onset was young children and adolescents. Hip, shoulder and ankle are more common, followed by knee, wrist and elbow joints. Due to the appearance of multiple irregular bone centers, the epiphysis increases, sometimes extending to the backbone. Later, the ossification center was irregularly fused, causing the joint surface to be uneven, leading to early osteoarthritis.